Miscellaneous
Paediatric Formulation Design and Development
Paediatric Formulation Design and Development
Source: http://www.mdpi.com/books
Edited by: Nunzio Denora and Antonio Lopalco
Introduction
When designing and developing paediatric medicines, the route of administration, dosage form, and dose of the active ingredient (API) are decided on the basis of the expected duration of the therapy, the disease affecting a patient and his/her age, size, physio-pathological condition, API organoleptic and physicochemical properties (taste, aqueous solubility), its pharmacokinetic and pharmacodynamic properties, and stability during manufacture, storage, and use of the chosen formulation.
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